ISCOMATRIX vaccines mediate CD8 + T‐cell cross‐priming by a MyD88‐dependent signaling pathway
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چکیده
منابع مشابه
ISCOMATRIX vaccines mediate CD8+ T-cell cross-priming by a MyD88-dependent signaling pathway
Generating a cytotoxic CD8(+) T-cell response that can eradicate malignant cells is the primary objective of cancer vaccine strategies. In this study we have characterized the innate and adaptive immune response to the ISCOMATRIX adjuvant, and the ability of vaccine antigens formulated with this adjuvant to promote antitumor immunity. ISCOMATRIX adjuvant led to a rapid innate immune cell respon...
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ژورنال
عنوان ژورنال: Immunology & Cell Biology
سال: 2011
ISSN: 0818-9641,1440-1711
DOI: 10.1038/icb.2011.71